Transsexual people experience a gender identity that is inconsistent with, or not culturally associated with, their assigned sex and desire to permanently transition to the gender with which they identify, usually seeking medical assistance including hormone replacement therapy and other sex reassignment therapies to help them align their body with their identified sex or gender. Transsexual is a subset of transgender ,    but some transsexual people reject the label of transgender. Norman Haire reported that in ,  Dora R of Germany began a surgical transition, under the care of Magnus Hirschfeld , which ended in with a successful genital reassignment surgery. In , Hirschfeld supervised the second genital reassignment surgery to be reported in detail in a peer-reviewed journal, that of Lili Elbe of Denmark.
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North of England correspondent sallylockwood. Hundreds of young transgender people are seeking help to return to their original sex, a woman who is setting up a charity has told Sky News. Charlie Evans, 28, was born female but identified as male for nearly 10 years before detransitioning. The number of young people seeking gender transition is at an all-time high but we hear very little, if anything, about those who may come to regret their decision. There is currently no data to reflect the number who may be unhappy in their new gender or who may opt to detransition to their biological sex. Charlie detransitioned and went public with her story last year - and said she was stunned by the number of people she discovered in a similar position.
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